Welcome to the Institute for Biomedical Engineering, Department of Cell Biology, Faculty of Medicine of RWTH Aachen University and RWTH Aachen University Hospital, Helmholtz Institute for Biomedical Engineering, Rheinisch Westfälische Technische Hochschule, RWTH Aachen University, Aachen, Germany.
The institute is part of the Helmholtz Institute for Biomedical Engineering, an interdisciplinary institute of the Faculty of Mathematics, Computer Science and Natural Sciences, Faculty of Mechanical Engineering, Faculty of Electrical Engineering and Information Technology and the Faculty of Medicine of RWTH Aachen University, Aachen, Germany. The founding director of the institute is Martin Zenke, PhD, Professor of Cell Biology (CV), who heads the institute since 2003.
The institute studies stem cells and their differentiated progeny. This includes adult stem cells, such as hematopoietic and mesenchymal stem cells, and embryonic stem cells (ES cells). We also study engineered stem cells, such as induced pluripotent stem cells (iPS cells), and use precision genome engineering with CRISPR/Cas to generate cells with desired properties.
Stem cells are differentiated into a large array of terminally differentiated cell types with a focus on antigen presenting dendritic cells. Additionally, iPS cells are differentiated into mesenchymal cells, endothelial cells, mast cells and megakaryocytes, which are used for disease modelling and compound screening.
Institute for Biomedical Engineering, Cell Biology
Aachen University Medical School
Pauwelstrasse 30, 52074 Aachen, Germany
Helmholtz Institute for Biomedical Engineering
Pauwelsstrasse 20, 52074 Aachen, Germany
Phone: +49-241 80 80760