Welcome to the Institute for Biomedical Engineering, Department of Cell Biology, Medical Faculty of RWTH and Aachen University Hospital, Helmholtz Institute for Biomedical Engineering, Rheinisch Westfälische Technische Hochschule, RWTH, Aachen, Germany.
Cell identity and developmental potential are determined by genetic programs. The laboratory studies genetic programs of hematopoietic stem and progenitor cells, and their differentiated progeny.
Stem cells and progenitor cells are isolated from human cord blood, bone marrow or peripheral blood and from mouse bone marrow, and cells are grown in vitro with specific cytokines. Cells are then induced to differentiate with yet another set of cytokine and/or differentiation factors. A particular focus is on studying mechanisms of genetic and epigenetic regulation, which impact on development of antigen presenting dendritic cells.
Institute for Biomedical Engineering, Cell Biology
Aachen University Medical School
Pauwelstrasse 30, 52074 Aachen, Germany
Helmholtz Institute for Biomedical Engineering
Pauwelsstrasse 20, 52074 Aachen, Germany
Phone: +49-241 80 80760